Who do we work with?
Our Working Groups
curently ongoing...
Research Projects
A broad overview of current research topics and projects.
Cheminformatics
Computational methods for chemistry.
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Virtual Drug Screening in the Chemical Space Accessible by Chemical Synthesis
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TACsy - Training Alliance for Computational systems chemistry
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MATOMIC - Mathematical Modelling for Microbial Community Induced Metabolic Diseases
Graph Theory
Graph theoretical approaches in bioinformatics: assembly, phylogeny and more.
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Algorithms for Reconstructing Evolutionary Relationships between Phylogenies: The Multi-Valued Case
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Precise Methods for Orthology Assessment in Large Data Sets Using Best Matches
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Approximate Graph Products
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Geometric representations and symmetries of graphs, maps and other discrete structures and applications in science
Proteins
Structure prediction, interaction prediction, functional analysis and more.
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SFB1423 Structural Dynamics of GPCR Activation and Signaling
RNA
RNA structure and regulation
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RNAProNet - Integration der Netzwerke aus RNA- und proteinbasierender Regulation
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SPP 1738 Emerging Roles of Non-Coding RNAs in Nervous System Development, Plasticity and Disease
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High-throughput structure probing of RNA based on specific ligation of cyclo-phosphate ends combined with deep sequencing
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Miniaturized armless tRNAs – function, interaction, modifications
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Molecular Morphology: Deep Phylogeny Using RNA Structures and Related Markers
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Computational Detection of Bacterial ncRNAs and their Targets
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Synthetic riboswitches: design of multi-ligand switches and novel regulatory principle
Genomics and Transcriptomics
Everything from new methods for assembly, genome wide alignments, to functional annotation and analysis.
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Synteny-Based Identification of Genomic Innovations in Insects
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Usage of relative timing of intron gain for phylogenetic analysis
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Refined Methods for Inference of Metazoan Phylogeny Using Mitochondrial Genome Arrangement Data
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Genotype-Phenotype Maps and Signatures of Selection in Genomic Sequences
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COIL-seq: Dissecting Cyanobacterial Chromosome Dynamics
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Long Non-Coding RNAs in Primate Brain Evolution
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Computational Methods for a Large Scale Annotation of Mitochondrial Genome
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Multi omics network integration in hematological cancers
Obesity and Metabolism
Cell metabolism, metagenomics and -bolomics of the human digestive system, regulation of obesity and more.
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SFB 1052 Obesity Mechanisms
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Improving prediction and detection of small proteins for functional analysis in a consortium resembling the functions of the human microbiome
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Mathematical Modelling for Microbial Community Induced Metabolic Diseases (MATOMIC)
Other
Artificial Intelligence and other research topics
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GRK 446: Knowledge Representation
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SECAI - School of Embedded Composite Artificial Intelligence