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curently ongoing...

Research Projects

Epigenetics

• MAGE - A Model of the Aging Epigenome
• Epigenetic inheritance
• Properties of histone modifications
• Epigenetic Memory
• Evolution of epigenetic regulation in beetles (Coleoptera)

Evolution of Life

• The modern RNA world: non-coding RNA-based genetic regulation as a prerequisite for the emergence of multicellular complexity (funded by the National Council of Science and Technology in Mexico
• Differential evolution of non-coding DNA across eukaryotes could lead towards different pathways of multicellular complexity (funded by the Max Planck Institute for Mathematics in the Sciences
• Investigation of the gene phylogeny of GPCRs and associated molecules

RNA-Protein Interaction

• Inference and structural analysis of RNA-protein binding motifs
• Evolution of Complex Translational Control Elements in the Innate Immune Response
• Unusual RNA-polymerases: reaction mechanism and substrate specificity of tRNA nucleotidyltransferases

Who do we work with?

Our Working Groups