Publications - Working papers

Please find below working papers of our group. Currently, we list 47 working papers. In the list are only not published papers present. If you look for a preprint of an already published paper you must look in the "Published papers" section. If you have problems accessing electronic information, please let us know:

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Simulation of Gene Family Histories

HERNANDEZ-ROSALES Maribel, WIESEKE Nicolas, HELLMUTH Marc, STADLER Peter

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BMC Bioinformatics 15(Suppl 3):A8 (2014)

Abstract


The reconstruction of the evolutionary history of large gene families has remained a hard and complex problem, which amounts to disentangling speciation events from gene duplication events. The evaluation of reconstruction algorithms is hampered, furthermore, by the lack of well-studied cases that could serve as a gold standard. We present here a simulation environment designed to generate large gene families with complex duplication histories on which reconstruction algorithms can be tested and software tools can be benchmarked.

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