Publications - Published papers

Please find below publications of our group. Currently, we list 454 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (access) is restricted to our local network and chosen collaborators. If you have problems accessing electronic information, please let us know:

©NOTICE: All papers are copyrighted by the authors; If you would like to use all or a portion of any paper, please contact the author.

Evolution of Fungal U3 snoRNAs: Structural Variation and Introns

Sebastian Canzler, Peter F. Stadler, Jana Hertel

Download


PREPRINT 16-018: [ PDF ]  [ Supplement ]

Status:


Non-Coding RNA 3.1 (2017): 3.

Abstract


The U3 snoRNA is an essential player in the initial steps of ribosomal RNA biogenesis which is ubiquitously present in Eukarya. It is exceptional among the small nucleolar RNAs in its size, the presence of multiple conserved sequence box, a highly conserved secondary structure core, its biogenesis as an independent pol-III gene, and its involvement in pre-rRNA cleavage rather than chemical modification. Fungal U3 snoRNAs share many features with their sisters from other eukaryotic kingdoms but differ in particular in their 5' regions, which in fungi has a distinctive consensus structure and often harbours introns. Here we report on a comprehensive homology search and detailed analysis of the evolution of sequence and secondary structure features covering the entire kingdom Fungi.

Keywords


small nucleolar RNA, pre-rRNA processing, RNA secondary structure, spliceosomal introns, RNA-RNA interactions, evolution