Publications - Published papers

Please find below publications of our group. Currently, we list 501 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (access) is restricted to our local network and chosen collaborators. If you have problems accessing electronic information, please let us know:

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Simulation of Gene Family Histories

HERNANDEZ-ROSALES Maribel, WIESEKE Nicolas, HELLMUTH Marc, STADLER Peter

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BMC Bioinformatics 15(Suppl 3):A8 (2014)

Abstract


The reconstruction of the evolutionary history of large gene families has remained a hard and complex problem, which amounts to disentangling speciation events from gene duplication events. The evaluation of reconstruction algorithms is hampered, furthermore, by the lack of well-studied cases that could serve as a gold standard. We present here a simulation environment designed to generate large gene families with complex duplication histories on which reconstruction algorithms can be tested and software tools can be benchmarked.

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