Publications - Published papers

Please find below publications of our group. Currently, we list 496 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (access) is restricted to our local network and chosen collaborators. If you have problems accessing electronic information, please let us know:

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<tt>CelloS</tt>: A Multi-level Approach to Evolutionary Dynamics

Camille Stephan-Otto Attolini, Peter F. Stadler, Christoph Flamm

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Status:


LNCS 3630: 500-509 (2005)

Abstract


We study the evolution of simple cells that are equipped with a genome, a rudimentary gene regulation network at transcription level and two classes of functional genes: motion effectors allow the cell to move in response to nutrient gradients while nutrient importers are required to actually feed from the environment. The model is inspired by the protist Naegleria gruberi which can switch between a feeding and dividing amoeboid state and a mobile flagellate state depending on environmental conditions. Simulation results demonstrate how selection in a variable environment affects the gene number and efficiency so that the cells can rapidly switch from one expression regime to the other depending on the external conditions.

Keywords


Artificial Cells, gene regulation, evolution, Naegleria gruberi

Note


Advances in Artificial Life: 8th European Conference, ECAL 2005., Mathieu S. Capcarrere, Alex A. Freitas, Peter J. Bentley, Colin G. Johnson, Jon Timmis (eds), Canterbury, UK, September 5-9, 2005