Publications - Published papers

Please find below publications of our group. Currently, we list 496 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (access) is restricted to our local network and chosen collaborators. If you have problems accessing electronic information, please let us know:

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Aggregation of Variables and System Decomposition: Applications to Fitness Landscape Analysis

Max Shpak, Peter F. Stadler, Günter P. Wagner, Joachim Hermisson

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Theory in Biosciences 123: 33-68 (2004)

Abstract


In this paper we present general results on aggregation of variables, specifically as it applies to decomposable (partitionable) dynamical systems. We show that a particular class of transition matrices, namely, those satisfying an equitable partitioning property, are aggregable under appropriate decomposition operators. It is also shown that equitable partitions have a natural application to the description of mutation-selection matrices (fitness landscapes) when their fitness functions have certain symmetries concordant with the neighborhood relationships in the underlying configuration space. We propose that the aggregate variable descriptions of mutation-selection systems offer a potential formal definition of units of selection and evolution.

Keywords


Fitness Landscapes, Aggregation of Variables, Decomposability, Mutation, Selection

Note


Alternative Numbers: SFI Preprint 03-04-025