Publications - Published papers

Please find below publications of our group. Currently, we list 506 papers. Some of the publications are in collaboration with the group of Sonja Prohaska and are also listed in the publication list for her individual group. Access to published papers (access) is restricted to our local network and chosen collaborators. If you have problems accessing electronic information, please let us know:

©NOTICE: All papers are copyrighted by the authors; If you would like to use all or a portion of any paper, please contact the author.

Landscapes and Effective Fitness

Peter F. Stadler, Christopher R. Stephens

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PREPRINT 02-006: [ PDF ]  [ PS ]
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Status:


Comments Theor. Biol. 8: 389-431 (2003)

Abstract


The concept of a fitness landscape arose in theoretical biology, while that of effective fitness has its origin in evolutionary computation. Both have emerged as useful conceptual tools with which to understand the dynamics of evolutionary processes, especially in the presence of complex genotype-phenotype relations. In this contribution we attempt to provide a unified discussion of these two approaches, discussing both their advantages and disadvantages in the context of some simple models. We also discuss how fitness and effective fitness change under various transformations of the configuration space of the underlying genetic model, concentrating on coarse graining transformations and on a particular coordinate transformation that provides an appropriate basis for illuminating the structure and consequences of recombination.

Keywords


fitness landscapes, effective fitness, quasispecies, recombination, population genetics, evolutionary computation

Note


Alternative Numbers: SFI 02-11-062, TBI 02-pfs-012