Table S23: Modification sites that are found to be
guided by at least two distinct box H/ACA snoRNA families. A
particular modification is considered if at least 10 different
interactions are predicted with a cumulated minimum free interaction
energy lower than -25 kcal/mol.
| modification site |
original name |
snoStrip name |
hairpin |
ICI_sno score |
ICI_sub score |
mean mfe [kcal/mol] |
# interactions |
| 18S-1198 |
snR10 |
HACA_13 |
HP2 |
0.10 |
0.38 |
-38.51 |
11/131(8.40%) |
| Nc_HACA_2 |
HACA_2 |
HP2 |
0.34 |
0.41 |
-26.14 |
23/82(28.05%) |
| 18S-1226 |
snR80 |
HACA_37 |
HP2 |
0.34 |
0.35 |
-32.67 |
28/100(28.00%) |
| snR8 |
HACA_6 |
HP2 |
0.20 |
0.43 |
-27.03 |
16/100(16.00%) |
| Nc_HACA_8 |
HACA_8 |
HP2 |
0.25 |
0.27 |
-28.86 |
12/57(21.05%) |
| 18S-1318 |
snR35 |
HACA_34 |
HP1 |
0.94 |
0.94 |
-37.14 |
56/77(72.73%) |
| snR46 |
HACA_35 |
HP2 |
0.55 |
0.94 |
-29.65 |
28/69(40.58%) |
| 18S-1418 |
snR80 |
HACA_37 |
HP1 |
0.14 |
0.15 |
-25.69 |
12/100(12.00%) |
| Nc_HACA_4 |
HACA_4 |
HP1 |
0.15 |
0.17 |
-36.86 |
11/89(12.36%) |
| 18S-1582 |
snR191 |
HACA_42 |
HP1 |
0.49 |
0.49 |
-27.91 |
52/125(41.60%) |
| AJ632016 |
HACA_53 |
HP2 |
0.21 |
0.23 |
-42.08 |
12/68(17.65%) |
| 18S-342 |
snR49 |
HACA_29 |
HP2 |
0.92 |
0.92 |
-29.32 |
17/22(77.27%) |
| AJ632016 |
HACA_53 |
HP2 |
0.34 |
0.38 |
-41.02 |
19/68(27.94%) |
| 18S-400 |
snR10 |
HACA_13 |
HP1 |
0.19 |
0.20 |
-31.81 |
20/131(15.27%) |
| Nc_HACA_15 |
HACA_15 |
HP1 |
0.39 |
0.39 |
-37.36 |
21/69(30.43%) |
| snR35 |
HACA_34 |
HP1 |
0.41 |
0.43 |
-31.85 |
29/77(37.66%) |
| Nc_HACA_4 |
HACA_4 |
HP2 |
0.23 |
0.30 |
-27.89 |
17/89(19.10%) |
| 18S-421 |
snR10 |
HACA_13 |
HP2 |
0.22 |
0.23 |
-31.46 |
25/131(19.08%) |
| snR34 |
HACA_28 |
HP2 |
0.12 |
0.13 |
-34.47 |
11/105(10.48%) |
| AJ632016 |
HACA_53 |
HP2 |
0.25 |
0.25 |
-40.21 |
14/68(20.59%) |
| 18S-964 |
Nc_HACA_2 |
HACA_2 |
HP1 |
0.85 |
0.85 |
-27.01 |
50/82(60.98%) |
| snR35 |
HACA_34 |
HP1 |
0.17 |
0.17 |
-33.98 |
12/77(15.58%) |
| 25S-1140 |
snR10 |
HACA_13 |
HP1 |
0.14 |
0.17 |
-34.27 |
11/131(8.40%) |
| snR80 |
HACA_37 |
HP1 |
0.49 |
0.76 |
-25.19 |
27/100(27.00%) |
| 25S-1862 |
snR85 |
HACA_17 |
HP1 |
0.48 |
0.48 |
-26.68 |
28/100(28.00%) |
| snR191 |
HACA_42 |
HP1 |
0.16 |
0.16 |
-31.82 |
12/125(9.60%) |
| 25S-1934 |
snR32 |
HACA_21 |
HP2 |
0.40 |
0.40 |
-28.16 |
24/101(23.76%) |
| snR191 |
HACA_42 |
HP1 |
0.17 |
0.19 |
-26.96 |
14/125(11.20%) |
| 25S-1962 |
Nc_HACA_4 |
HACA_4 |
HP1 |
0.44 |
0.58 |
-32.14 |
23/89(25.84%) |
| snR43 |
HACA_9 |
HP1 |
1.17 |
1.17 |
-31.85 |
62/95(65.26%) |
| 25S-2597 |
snR10 |
HACA_13 |
HP2 |
0.29 |
0.36 |
-32.91 |
23/131(17.56%) |
| snR35 |
HACA_34 |
HP2 |
0.20 |
0.20 |
-30.70 |
11/77(14.29%) |
| 25S-2813 |
snR32 |
HACA_21 |
HP2 |
0.36 |
1.07 |
-26.18 |
19/101(18.81%) |
| snR34 |
HACA_28 |
HP2 |
0.19 |
0.20 |
-32.13 |
14/105(13.33%) |
| AJ632016 |
HACA_53 |
HP2 |
0.40 |
0.45 |
-41.03 |
17/68(25.00%) |
| 25S-290 |
snR191 |
HACA_42 |
HP1 |
0.34 |
0.34 |
-31.20 |
15/125(12.00%) |
| Nc_HACA_8 |
HACA_8 |
HP2 |
0.97 |
1.01 |
-30.97 |
22/57(38.60%) |
| 25S-3013 |
Nc_HACA_2 |
HACA_2 |
HP1 |
1.07 |
1.07 |
-28.54 |
42/82(51.22%) |
| snR191 |
HACA_42 |
HP1 |
0.14 |
0.17 |
-28.65 |
11/125(8.80%) |
| 25S-3017 |
snR191 |
HACA_42 |
HP1 |
0.14 |
0.14 |
-28.87 |
11/125(8.80%) |
| snR8 |
HACA_6 |
HP2 |
0.22 |
0.20 |
-30.73 |
13/100(13.00%) |
| 25S-3061 |
Nc_HACA_11 |
HACA_11 |
HP1 |
0.21 |
0.21 |
-27.94 |
12/85(14.12%) |
| AJ632016 |
HACA_53 |
HP2 |
0.26 |
0.64 |
-44.43 |
11/68(16.18%) |
| snR43 |
HACA_9 |
HP1 |
0.27 |
0.43 |
-26.83 |
18/95(18.95%) |
| 25S-3315 |
snR34 |
HACA_28 |
HP2 |
0.24 |
0.26 |
-36.04 |
18/105(17.14%) |
| Nc_HACA_3 |
HACA_3 |
HP2 |
0.90 |
0.90 |
-33.45 |
61/116(52.59%) |
| 25S-3355 |
snR85 |
HACA_17 |
HP1 |
0.59 |
0.59 |
-26.12 |
33/100(33.00%) |
| snR191 |
HACA_42 |
HP1 |
0.18 |
0.19 |
-27.65 |
15/125(12.00%) |
| 25S-3449 |
snR34 |
HACA_28 |
HP2 |
0.34 |
0.37 |
-35.29 |
25/105(23.81%) |
| Nc_HACA_3 |
HACA_3 |
HP2 |
1.03 |
1.03 |
-31.31 |
70/116(60.34%) |
| 25S-3570 |
Nc_HACA_15 |
HACA_15 |
HP1 |
0.44 |
0.44 |
-39.26 |
16/69(23.19%) |
| snR43 |
HACA_9 |
HP1 |
0.51 |
0.53 |
-26.36 |
33/95(34.74%) |
| 25S-3615 |
snR85 |
HACA_17 |
HP1 |
0.36 |
0.36 |
-33.52 |
18/100(18.00%) |
| snR44 |
HACA_1 |
HP1 |
0.76 |
0.82 |
-27.04 |
44/109(40.37%) |
| 25S-3617 |
snR85 |
HACA_17 |
HP1 |
0.60 |
0.71 |
-29.93 |
29/100(29.00%) |
| Nc_HACA_3 |
HACA_3 |
HP2 |
0.21 |
0.22 |
-27.21 |
16/116(13.79%) |
| 25S-4073 |
snR10 |
HACA_13 |
HP1 |
0.34 |
0.34 |
-33.19 |
26/131(19.85%) |
| snR34 |
HACA_28 |
HP2 |
0.28 |
0.30 |
-35.29 |
20/105(19.05%) |
| Nc_HACA_3 |
HACA_3 |
HP2 |
0.20 |
0.20 |
-31.70 |
16/116(13.79%) |
| 25S-4084 |
Nc_HACA_19 |
HACA_19 |
HP2 |
0.38 |
0.42 |
-36.96 |
13/60(21.67%) |
| snR46 |
HACA_35 |
HP1 |
1.19 |
1.21 |
-31.72 |
48/69(69.57%) |
| Nc_HACA_3 |
HACA_3 |
HP2 |
0.18 |
0.18 |
-27.56 |
14/116(12.07%) |
| 25S-787 |
snR10 |
HACA_13 |
HP2 |
0.32 |
0.40 |
-30.70 |
24/131(18.32%) |
| Nc_HACA_2 |
HACA_2 |
HP2 |
0.89 |
0.93 |
-28.31 |
40/82(48.78%) |
| 5.8S-18 |
snR85 |
HACA_17 |
HP2 |
0.14 |
0.19 |
-28.55 |
11/100(11.00%) |
| snR34 |
HACA_28 |
HP2 |
0.34 |
0.34 |
-33.31 |
32/105(30.48%) |
| snR191 |
HACA_42 |
HP1 |
0.60 |
0.60 |
-30.36 |
62/125(49.60%) |
| Nc_HACA_8 |
HACA_8 |
HP2 |
1.02 |
1.10 |
-32.44 |
45/57(78.95%) |
| 5.8S-27 |
snR85 |
HACA_17 |
HP1 |
0.41 |
0.41 |
-27.93 |
33/100(33.00%) |
| AJ632016 |
HACA_53 |
HP2 |
0.20 |
0.22 |
-39.88 |
12/68(17.65%) |
| U1-139 |
Nc_HACA_3 |
HACA_3 |
HP2 |
0.26 |
0.90 |
-31.58 |
20/116(17.24%) |
| Nc_HACA_8 |
HACA_8 |
HP2 |
0.19 |
0.21 |
-27.94 |
11/57(19.30%) |
| U2-123 |
snR34 |
HACA_28 |
HP2 |
0.15 |
0.23 |
-36.10 |
13/105(12.38%) |
| Nc_HACA_3 |
HACA_3 |
HP2 |
0.16 |
0.18 |
-31.96 |
16/116(13.79%) |
| U2-67 |
Nc_HACA_19 |
HACA_19 |
HP1 |
0.26 |
0.26 |
-32.79 |
15/60(25.00%) |
| snR8 |
HACA_6 |
HP1 |
0.14 |
0.18 |
-25.25 |
12/100(12.00%) |
| U4-41 |
snR32 |
HACA_21 |
HP1 |
0.18 |
0.23 |
-25.52 |
14/101(13.86%) |
| snR32 |
HACA_21 |
HP2 |
0.35 |
0.35 |
-25.49 |
30/101(29.70%) |
| U6-49 |
snR80 |
HACA_37 |
HP1 |
0.32 |
0.33 |
-27.20 |
27/100(27.00%) |
| snR191 |
HACA_42 |
HP1 |
0.12 |
0.15 |
-27.77 |
15/125(12.00%) |
| snR36 |
HACA_43 |
HP2 |
0.14 |
0.14 |
-25.57 |
12/99(12.12%) |
| U6-61 |
snR35 |
HACA_34 |
HP1 |
0.19 |
0.25 |
-32.32 |
14/77(18.18%) |
| snR46 |
HACA_35 |
HP2 |
0.20 |
0.32 |
-26.62 |
14/69(20.29%) |
| U6-79 |
Nc_HACA_11 |
HACA_11 |
HP1 |
0.16 |
0.16 |
-27.05 |
13/85(15.29%) |
| snR10 |
HACA_13 |
HP2 |
0.12 |
0.16 |
-33.80 |
15/131(11.45%) |
| Nc_HACA_15 |
HACA_15 |
HP2 |
0.28 |
0.28 |
-27.82 |
18/69(26.09%) |
| U6-85 |
snR35 |
HACA_34 |
HP1 |
0.30 |
0.30 |
-31.54 |
22/77(28.57%) |
| snR46 |
HACA_35 |
HP2 |
0.32 |
0.51 |
-26.42 |
21/69(30.43%) |
| snR191 |
HACA_42 |
HP2 |
0.15 |
0.27 |
-39.70 |
18/125(14.40%) |