**Table S13:** Box C/D snoRNA families with a conserved D' target. The amount of snoRNAs that were found to belong to this family are given in the second column. Information about the most conserved targets for box D' and box D are given in their respective columns. Lineages in which the predicted D' target interaction is present are denoted in column 'conservation' Legend at the bottom. There is no conservation information for D targets since these are mostly genus, family, or species-specific. The 'verified' column states whether this target was previously published or not.
original name	# sequences	box	aln pos	sce pos	ICI_sno	mean mfe	conservation	verified	`snoStrip` name
snR13	111	D'	25S-3465	25S-2280	0,90	-14,87	4,6	+	CD_1
snR13	111	D	U6-54	U6-51	0,16	-8,58		-	CD_1
snR66	126	D'	25S-3611	25S-2417	1,21	-18,84	3..6	+	CD_2
snR66	126	D	25S-3856	25S-2639	0,16	-18,63		-	CD_2
Nc_CD_3	68	D'	25S-4101	25S-2882	1,24	-19,52	10,11	+	CD_3
Nc_CD_3	68	D	18S-1395	18S-1266	0,17	-12,95		-	CD_3
Nc_CD_4	51	D'	18S-55	18S-49	1,67	-22,18	7,11	+	CD_4
Nc_CD_4	51	D	U6-72	U6-68	0,29	-19,51		-	CD_4
snR75	119	D'	25S-3474	25S-2288	1,19	-17,76	3..6	+	CD_7
snR75	119	D	5.8S-150	5.8S-139	0,39	-10,82		-	CD_7
snR48	103	D'	25S-4012	25S-2793	1,49	-24,47	3,8	+	CD_8
snR48	103	D	18S-1343	18S-1215	0,46	-9,24		-	CD_8
Nc_CD_14	117	D'	25S-3512	25S-2326	0,91	-18,09	3..6	+	CD_14
Nc_CD_14	117	D	U5-15	U5-13	0,10	-10,60		-	CD_14
Nc_CD_15	68	D'	18S-179	18S-162	1,09	-17,22	11	+	CD_15
Nc_CD_15	68	D	18S-1401	18S-1272	0,29	-11,27		-	CD_15
snR190	70	D'	25S-3588	25S-2395	0,69	-19,96	4,10,11	+	CD_16
snR190	70	D	25S-1571	25S-609	0,09	-21,23		-	CD_16
snR74	116	D'	18S-33	18S-28	0,93	-18,72	3,6	+	CD_21
snR74	116	D	18S-1406	18S-1277	0,18	-10,62		-	CD_21
snR38	128	D'	25S-4034	25S-2815	1,43	-21,94	3,4,6	+	CD_23
snR38	128	D	18S-1091	18S-982	0,14	-9,99		-	CD_23
snR77	109	D'	18S-630	18S-578	1,36	-17,27	3..6	+	CD_24
snR77	109	D	18S-1478	18S-1348	0,40	-9,73		-	CD_24
Nc_CD_25	54	D'	25S-1856	25S-866	1,40	-27,76	11	+	CD_25
Nc_CD_25	54	D	5.8S-14	5.8S-13	0,17	-16,50		-	CD_25
snR71	134	D'	25S-4182	25S-2946	1,31	-21,33	4..6	+	CD_27
snR71	134	D	25S-1141	25S-355	0,09	-7,50		-	CD_27
Nc_CD_30	73	D'	18S-640	18S-587	1,53	-18,32	Puc,11	+	CD_30
Nc_CD_30	73	D	U6-84	U6-79	0,07	-7,72		-	CD_30
snR73	126	D'	25S-4198	25S-2959	1,58	-23,23	3..6	+	CD_31
snR73	126	D	18S-1696	18S-1495	0,15	-16,39		-	CD_31
snR64	121	D'	25S-3526	25S-2337	1,15	-18,43	6	+	CD_36
snR64	121	D	18S-976	18S-873	0,11	-11,50		-	CD_36
snR61	131	D'	25S-2148	25S-1133	1,19	-18,20	3,6	+	CD_38
snR61	131	D	25S-2494	25S-1437	0,08	-15,34		-	CD_38
Nc_CD_39	124	D'	25S-1907	25S-917	1,10	-17,48	4,6	+	CD_39
Nc_CD_39	124	D	18S-265	18S-236	0,12	-13,34		-	CD_39
U18	153	D'	25S-1614	25S-649	1,32	-23,20	3,4,6	+	CD_46
U18	153	D	18S-475	18S-432	0,19	-10,33		-	CD_46
snR69	144	D'	25S-4185	25S-2948	0,97	-20,26	4,6	+	CD_56
snR69	144	D	18S-915	18S-816	0,07	-13,58		-	CD_56
snR70	102	D'	18S-1843	18S-1639	1,48	-17,82	6	+	CD_61
snR70	102	D	18S-1272	18S-1148	0,37	-7,99		-	CD_61
snR68	16	D'	25S-3857	25S-2640	1,49	-18,79	10	+	CD_65
snR68	16	D	25S-2224	25S-1207	0,81	-14,66		-	CD_65
snR65	7	D'	25S-3536	25S-2347	1,65	-16,96	Sacch	+	CD_66
snR65	7	D	25S-3512	25S-2326	0,52	-19,90		-	CD_66
snR58	85	D'	25S-1628	25S-663	1,28	-20,39	6-15	+	CD_68
snR58	85	D	25S-2132	25S-1117	0,10	-12,77		-	CD_68
LSU-C2809	8	D'	25S-4055	25S-2836	1,81	-21,73	10	+	CD_69
LSU-C2809	8	D	25S-3965	25S-2748	0,29	-9,80		-	CD_69

Conservation of target interactions: 1) Fungi 2) Microsporidia 3) Mucoromycotina 4) Chytridiomycota 5) Blastocladiomycota 6) Dikarya 7) Basidiomycota 8) Asomycota 9) Taphrinomycotina 10) Saccharomycotina 11) Pezizomycotina 12) Dothideomycetes 13) Eurotiomycetes 14) Leotiomycetes 15) Sordariomycetes Puc) Pucciniomycotina Sacch) Saccharomycetaceae Neuro) Neurospora 3..6) equals 3,4,5,6 6-15) equals 6 without 15