Structure prediction of UnaL2 LINE 3' element


Comparison of the NMR derived reference (Rfam) structure of UnaL2 LINE 3' element and predicted structures. Using the original hamming distance covariance scoring of RNAalifold, the stem is not correctly predicted. This is due to a small number of counter examples in some of the base pairs of the stem (shown in pale below).

The RIBOSUM variant of RNAalifold predicts the main stem correctly, and is only wrong in the prediction of where the bulges are at the bottom of the stem.

Reference Structure of UnaL2 LINE 3' element

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Reference Alignment of UnaL2 LINE 3' element

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Structure using the original RNAalifold

Image HACAsnosnakeoriginal

Alignment of UnaL2 LINE 3' element

original RNAalifold structure
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Structure using RIBOSUM RNAalifold

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Alignment of UnaL2 LINE 3' element

RIBOSUM RNAalifold structure
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