Bioinformatics Preprint 05-024
Local Base Pairing Probabilities in Large RNAs
Stephan Bernhart, Ivo L. Hofacker, Peter F. Stadler,
The genome-wide search for non-coding RNAs requires efficient methods to compute and compare local secondary structures. Since the exact boundaries of such putative transcripts are typically unknown, arbitrary sequence windows have to be used in practice. Here we present a method for robustly computing the probabilities of local base pairs from long RNA sequences independent of the exact positions of the sequence window.
Keywords: RNA secondary structure, folding algorithms, base pairing probabilities
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Last modified: 2005-10-30 21:12:46 studla