Inst. f. Informatik   
Uni Leipzig

Bioinformatics Preprint 03-010

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The Shark HoxN cluster is homologous to the Human HoxD cluster

Sonja J. Prohaska, Claudia Fried, Chris T. Amemiya, Frank H. Ruddle, Günter P. Wagner, Peter F. Stadler

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The statistical analysis of phylogenetic footprints in the two known horn shark Hox clusters and the four mammalian clusters shows that the shark HoxN cluster is HoxD-like. This finding implies that the most recent common ancestor of jawed vertebrates had at least four Hox clusters, including those which are orthologous to the four mammalian Hox clusters.

Hox clusters, phylogenetic footprints

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Last modified: 2003-04-30 19:53:53 studla