Inst. f. Informatik   
Uni Leipzig

Bioinformatics Preprint 03-010

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Titel:
The Shark HoxN cluster is homologous to the Human HoxD cluster

Author(s):
Sonja J. Prohaska, Claudia Fried, Chris T. Amemiya, Frank H. Ruddle, Günter P. Wagner, Peter F. Stadler

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Abstract:
The statistical analysis of phylogenetic footprints in the two known horn shark Hox clusters and the four mammalian clusters shows that the shark HoxN cluster is HoxD-like. This finding implies that the most recent common ancestor of jawed vertebrates had at least four Hox clusters, including those which are orthologous to the four mammalian Hox clusters.

Keywords:
Hox clusters, phylogenetic footprints

Alternative Numbers:


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Last modified: 2003-04-30 19:53:53 studla